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Pearl Tomato®: Clinical Study Summary

Written by Vesta Contract Manufacturing Team | Oct 24, 2025 8:21:41 PM

What is Pearl Tomato®?

Pearl Tomato® is a natural supplement designed to help brighten and even out skin tone. A 90-day clinical study tested how well it works for improving skin brightness, smoothness, and overall appearance in adults aged 18 to 50. The study compared people who took Pearl Tomato® with those who took a placebo (a capsule with no active ingredient).

Key Results

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  • Brighter and more even skin tone: Participants who took Pearl Tomato® showed visible improvements in brightness and evenness within 60 to 90 days, compared to the placebo group.
  • Smoother texture: Skin felt softer and smoother, with fewer rough patches or uneven areas.
  • Less dark spots and redness: There was a noticeable reduction in dark spots and redness, helping skin look clearer and more radiant.
  • GMOs are genetically modified organisms created using genetic engineering techniques, raising concerns among scientists, consumers, and environmental groups.
  • Healthier glow:  Dermatologists noted a healthy, natural glow and improved clarity over time.
  • Safe and well-tolerated: No negative side effects were reported, and skin maintained normal elasticity and hydration levels. 

How it Works

The study also found that Pearl Tomato® helped lower the level of tyrosinase, a natural enzyme that affects how much pigment (melanin) your skin produces. Lower tyrosinase means a lighter, more even complexion over time.

About the Study

  • Conducted by dermatologists in a controlled, 90-day study.
  • Included men and women aged 18–50 with different skin types.
  • Participants were randomly assigned to take either Pearl Tomato® or a placebo.
  • Skin was evaluated at four time points (Day 15, 30, 60, and 90) using dermatologist assessments and imaging tools.

Key Assessments & Statistically Significant Endpoints (p < 0.05)

  • Skin Tone, Hyperpigmentation & Radiance
    • Brightness & clarity: Strong within-group improvement (p = 0.001)
    • Tactile smoothness: Significant improvement (p = 0.001)
    • Skin tone evenness: Earlier and consistent improvement vs. placebo
  • Visual Dermatologist Assessment
    • Skin brightness: Significant improvement(p = 0.001)
    • Skin smoothness: Sustained improvement (p < 0.001)
    • Skin clarity & color: Progressive improvement (p = 0.001)
    • Hyperpigmentation: Earlier and more pronounced reduction
    • Glow & radiance: Significant enhancement by Day 60 & 90
  • Instrumental Assessments
    • Tyrosinase biomarker: Reduced from 537.0 to 446.5 (p = 0.003)
    • Melanin index: ~6% reduction
    • Erythema: Trend toward reduction
    • Elasticity: Maintained firmness and biomechanical integrity

In summary, Pearl Tomato® Clinical Research:

An overall pattern of results for enhanced skin brightness and clarity with Pearl Tomato® supplementation.

Pearl Tomato® supplementation demonstrated statistically significant and sustained improvements in skin tone, brightness, smoothness, and clarity, with strong dermatological and instrumental support. It is a promising intervention for skin health enhancement.

Study Tools Used

  • A dermatologist applied Griffiths' 10-point scale, the Global Aesthetic Improvement Scale
  • Instrument Visioface 1000D imaging, and DermaLab Colori probes with TEWL (Trans Epidermal Water Loss), Elasticity, and Hydration
  • Hematologic Test for Tyrosinase Biomarker Analysis

Study Design:  Randomized, double-blind, placebo-controlled trial in healthy adults (18–50 years) assessing skin brightening, pigmentation, and overall skin health over 90 days. 

This clinical trial has been registered within an international Clinical Trials Registry.

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